Endpoints: 28,729MCP servers: 18,413Payout addresses: 2,071Paid calls: 1,545Letters: 14Defects: 1,324counted just now
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MCP serverai.nullary/nullary

Negative results intelligence for drug discovery — query measured failures via MCP.
UNRATEDActivestreamable-httpmcp.nullary.ai

Overview

Score?
UNRATED 0.718
of what a free look can see, on 31 looks
Looks
36
last 13 hr ago
Tools
35

More info

URL
mcp.nullary.ai/mcp
streamable-http
Says it is
Nullary 1.0.1
protocol 2025-06-18
In the record since
32 days ago

Among servers18,413 with a card

0median 0.606 · this server 0.718 · highest on record 0.8561

Toolsfrom sha256:2b9bfaeb3e…d46269

The tools this server lists, read out of the definition it returned
ToolSchema
get_compound
A compound (structure, name, max clinical phase) + its full negative profile across modalities/sources.
 input · output
get_coverage
Per-modality and per-source coverage stats (honest Phase-1 numbers).
 input · output
get_finding_provenance
Full provenance + detail for a single finding by id.
 input · output
get_model_card
Per-target Layer-1 model card: training counts and held-out scaffold-split metrics (ROC-AUC, PR-AUC, Brier, calibration). Accepts a gene symbol (e.g. EGFR) or UniProt accession (e.
 input · output
get_target_landscape
Target 'graveyard' / exhaustion index: how many distinct compounds/agents have been tried against a target and failed, broken down by modality and outcome. Answers 'how picked-over
 input · output
list_models
Summary of the Layer-1 inactivity-scoring model registry: how many per-target models, split by family, and median scaffold-split ROC-AUC.
 input · output
list_top_targets
Coverage browse: the most heavily-pursued ('graveyard') targets, ranked by recorded negative findings. Optional family filter (kinase, gpcr, protease, nuclear_receptor, ion_channel
 input · output
search_adc_linker_failures
ADC failures attributed to linker chemistry.
 input · output
search_admet_failures
Small-molecule ADMET failures.
 input · output
search_admet_failures_all_modalities
ADMET failures across ALL modalities.
 input · output
search_ancestry_specific_failures
Ancestry-specific CRISPR failures.
 input · output
search_bispecific_format_failures
Bispecific format/engineering failures.
 input · output
search_developability_failures
Antibody developability failures.
 input · output
search_drug_drug_interaction_failures
Drug-drug interaction failures.
 input · output
search_failed_adcs
ADCs that failed at any stage.
 input · output
search_failed_bispecifics
Bispecifics that failed at any stage.
 input · output
search_failed_clinical_antibodies
Discontinued/terminated clinical antibodies.
 input · output
search_failed_essentiality_screens
Non-dependency / failed essentiality screens.
 input · output
search_failed_guides
Failed/ineffective CRISPR guides.
 input · output
search_failed_oligonucleotides
ASOs/siRNAs that failed engagement/developability.
 input · output
search_failed_peptide_therapeutics
Failed peptide therapeutics.
 input · output
search_failed_protacs
PROTACs that failed degradation/ternary/permeability.
 input · output
search_failed_replications
Findings that failed to replicate.
 input · output
search_failed_selectivity
Small molecules that failed selectivity.
 input · output
search_failed_vaccines
Failed/terminated vaccines (by pathogen/indication).
 input · output
search_inactive_compounds
Inactive small-molecule compound-target pairs.
 input · output
search_indication_history
ALL failed approaches for an indication across every modality.
 input · output
search_mechanism_failures
Approaches that failed for a mechanism (by target).
 input · output
search_oligo_delivery_failures
Oligonucleotide delivery failures.
 input · output
search_pathogen_history
Vaccine + antimicrobial + antibody failures for a pathogen.
 input · output
search_peptide_stability_issues
Peptide stability/half-life failures.
 input · output
search_protac_e3_issues
PROTAC E3-ligase recruitment / ternary failures.
 input · output
search_safety_failures
Clinical/preclinical safety failures across modalities.
 input · output
search_target_history
ALL failed approaches against a target across every modality.
 input · output
search_vaccine_immunogenicity_failures
Failed vaccine immunogen designs.
 input · output
Verify it yourselfnpx teppi-check https://mcp.nullary.ai/mcpcurl -s https://api.teppi.xyz/v1/trust/mcp/mcs_01M1FZ22EA9WJ6KQPQ6BZ0Y4BA