MCP serverio.github.cyanheads/ensembl-mcp-server
Look up genes, sequences, variants, homologs, and cross-database xrefs from Ensembl REST.
Overview
Score?
UNRATED 0.679
of what a free look can see, on 30 looks
Looks
35
last 15 hr ago
Tools
7
changed 9 days ago
More info
URL
ensembl.caseyjhand.com/mcp
streamable-http
Says it is
ensembl-mcp-server 0.5.0
protocol 2025-06-18
In the record since
32 days ago
Among servers18,413 with a card
0median 0.606 · this server 0.679 · highest on record 0.8561
Toolsfrom sha256:b17d4635b5…24c113 · +0 −0 9 days ago
| Tool | Schema |
|---|---|
| ensembl_get_homology Find orthologs and/or paralogs of a gene across species. Returns each homolog's stable ID, species, homology type (ortholog_one2one, ortholog_one2many, paralog_many2many, etc.), pe |
input · output |
| ensembl_get_sequence Fetch the DNA, cDNA, CDS, or protein sequence for a gene, transcript, protein, or genomic region. Returns a window of the sequence — the first 10,000 characters by default — with i |
input · output |
| ensembl_get_xrefs Retrieve cross-database references for a gene or feature — HGNC, UniProt, EntrezGene, OMIM, RefSeq, Reactome, and others. Returns each xref with its database name, primary ID, disp |
input · output |
| ensembl_list_species List species supported by Ensembl with display name, common name, assembly, taxon ID, and division. Required discovery step — species names like homo_sapiens are opaque to non-biol |
input · output |
| ensembl_lookup_gene Resolve a gene by symbol + species (or by stable ID) to its Ensembl ID, genomic location (chr:start-end:strand), biotype, description, and transcript list. Entry point for most wor |
input · output |
| ensembl_predict_variant Predict the functional consequences of a sequence variant using the Ensembl Variant Effect Predictor (VEP). Accepts three input formats: HGVS notation (transcript-relative, e.g. EN |
input · output |
| ensembl_query_region Find genomic features overlapping a chromosomal region: genes, transcripts, variants, regulatory elements, or exons. Returns each feature with its stable ID, type, location, biotyp |
input · output |
Verify it yourself
npx teppi-check https://ensembl.caseyjhand.com/mcpcurl -s https://api.teppi.xyz/v1/trust/mcp/mcs_01M1FZ2ESN4DX9T0RWWE7W88QA