crispr-offtarget

Compares one guide with caller-supplied candidate protospacers, weights mismatches in the guide’s final ten positions twice, applies a simple NGG PAM penalty, and ranks a…

Compares one guide with caller-supplied candidate protospacers, weights mismatches in the guide’s final ten positions twice, applies a simple NGG PAM penalty, and ranks a transparent similarity score. It does not search a genome, model bulges, chromatin or nuclease-specific biology, and must not be used as a clinical or laboratory safety decision.

UNRATEDListed

Overview

Grade?

UNRATED

0 of 30 paid calls toward a letter

Price

$0.004 per call

Paid calls

none yet

delivery unknown until someone pays

More info

Seller?

0x2880edff…771c4e5e

URL

https://bio.halowerk.com/v1/crispr-offtarget

Seen

first 29 days ago · last 4 days ago

54 free handshakes

Payment

Pays through

x402

Offered on?

Base USDC

Listed on?

Base

Score, from free handshakes onlyweights 2026.09.6

UN
RATED

0.700 liveness verified, no letter

To a letter · 30 paid calls

0 of 30

Held back by sample size, not by the seller · gap to 1.000 is 0.300: 0.180 uncertain ? + 0.120 short ? · 0.100 to B

How the composite of 0.700 is made up, part by part
Component	Weight	Measured	Lower bound ?		Adds	Short ?	Uncertain ?
livenesscosts the most it answered at all	0.60	0.90	0.600		0.360	−0.062	−0.178
latency p95 it answered as fast as its class	0.20	0.71	0.701		0.140	−0.058	−0.002
price stability the price stayed where it was listed	0.20	1.00	1.000		0.200	0	0
Composite	1.00		0.700	gap to 1.000 = 0.300 · 0.120 short · 0.180 uncertain	0.700	−0.120	−0.180

Not measured: correctness · nobody paid; honesty · nobody paid; schema conformance · no answer had a published shape to check

The multiplication, written out

  0.600 × 0.600   liveness       
+ 0.200 × 0.701   latency p95    
+ 0.200 × 1.000   price stability
= 0.700           → UNRATED: 48 of 30 paid calls      weights 2026.09.6 · 48 samples · seed cap_01M1RDAEDSJ0EWMYH3J1KMA93P|2026-08-31T13:03:51.304Z|2026.09.6

Verify it yourselfnpx teppi-check https://bio.halowerk.com/v1/crispr-offtargetcurl -s https://api.teppi.xyz/v1/trust/cap_01M1RDAEDSJ0EWMYH3J1KMA93P